| abstract |
Compounds of formula (I) are antibacterial agents: wherein: Z is -N(OH)CH(=O) or -C(=O)NH(OH); R1 represents hydrogen, methyl or trifluoromethyl or, except when Z is a radical of formula -N(OH)CH(=O), a hydroxy, halo or amino group; R2, R3 and R4 independently represents hydrogen or a group R10-(D)n-(ALK)m- wherein R10 , D, n, m and ALK are as defined in the claims; or R3 and R4 taken together with the nitrogen atom to which they are attached form an optionally substituted monocyclic heterocyclic ring containing from 5 to 7 ring atoms, one of which is the nitrogen atom to which R4 and R5 are attached and the remaining ring atoms being selected from compatible combinations of carbon, oxygen, sulfur and nitrogen. |