Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ada0cee1a8b4ade7519bc3b90d23f5f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8a546c6ae8fc2012f662ca5ea468ad9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_396d5b4925b94d725489e67a006d2f08 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6901 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
filingDate |
2002-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_437325c9cac67b56d1166a5df63ca569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8fe47c7fa298709c77bcd8cf5b9943d |
publicationDate |
2003-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-03047650-A2 |
titleOfInvention |
Preparation of red blood cells having reduced immunogenicity |
abstract |
Methods are provided for the preparation of an RBC composition which has significantly reduced antigenicity. The methods of preparation of the red cell compositions involve the optimization of reaction conditions, in particular conditions, for attaching antigen masking compounds to the red cells without significantly affecting the function of the red cells. The RBC compositions are of particular use for introduction into an individual in cases where the potential for an immune reaction is high, for example in alloimmunized blood recipients or in trauma situations where the possibility of transfusion of a mismatched unit of blood is higher. The RBC compositions of this invention provide a much lower risk of a transfusion associated immune reaction. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10799533-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11235090-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11554185-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11096963-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004014973-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004014973-A3 |
priorityDate |
2001-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |