Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9f09696f61455fd8a5409d7cae240b68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_421840c68a1e8a8d90fadf3e33af4185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c4afb8b01aa8de7e0b24a86713b23a18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10f3248190c2c7628f71586e8e0636fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a283e5c9ef684af6cea587aeaf46961 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate |
2002-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f03e8b7148caefcfe45ce73380db8038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a943ddac029eeac62c63aef8cdfb7126 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8680e113a87d97e7fe4e7bfbbbd96894 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0a5a5b83aa2f0e070c568a6a359ecb0 |
publicationDate |
2003-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-03046579-A3 |
titleOfInvention |
Cyp46 genotype determination for risk and treatment evaluation of alzheimer's disease |
abstract |
Based on the unexpected identification of a CYP46 gene polymorphism as a novel genetic risk factor that links cholesterol metabolism to Alzheimer's disease, the present invention provides a method of diagnosing or prognosticating Alzheimer s disease, or determining the propensity or predisposition of a subject to develop Alzheimer s disease. The method comprises detecting the presence or absence of a variation in the CYP46 gene which encodes the enzyme cholesterol 24-hydroxylase. |
priorityDate |
2001-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |