http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03044228-A1

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filingDate 2002-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d74bedd419c5cebdeff95b9199607828
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publicationDate 2003-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-03044228-A1
titleOfInvention Improved primer discrimination method in allele-specific primer extension
abstract An improved primer discrimination method in allele-specific primer extension performed on a DNA chip is provided. The method uses a primer, which is to be immobilized on a surface or a solid support of the DNA chip, including in a 3' portion an allele-specific nucleotide complementary to an allelic variation nucleotide of a target nucleic acid to be assayed and at least one artificial mismatch nucleotide adjacent to the allele-specific nucleotide. The accuracy in base sequence analysis and mutant genotyping can be markedly improved. The method is effective in detecting a single point mutation as well as insertion and deletion variations.
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004108950-A3
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priorityDate 2001-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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