| abstract |
Remedies for dry eye and diseases associated with dry eye which contain as the active ingredient peptides represented by the following general formula (I) or pharmaceutically acceptable salts thereof: H-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg- X1-Gln-X2-Ala-Val-X3-X4-Tyr-Leu-X5-X6 (I) wherein X1, X3 and X4 represent each Lys or Arg; X2 represents Met, Leu or nLeu; X5 represents a chemical bond, Asn, Asn-Ser, Asn-Ser-Ile, Asn-Ser-Ile-Leu or Asn-Ser-Ile-Leu-Asn-X7 (wherein X7 represents a chemical bond, Gly, etc.); and X6 represents -OH or -NH2. |