Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_611c9127bdeaa8b7d6b23d334ffcf3e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6cf28e43ffae68c9a3bd1abe4524a7c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c785dea8e5ea8d2b18082d4d9a5a9da2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b081c9622bfd9f4d72b60ae4845112fb |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-382 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-352 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-382 |
filingDate |
2002-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95753ff1c2aa6289db9c16ff968c479c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfea3cc58c918df46167bbc62e639c91 |
publicationDate |
2003-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-03039538-A1 |
titleOfInvention |
Composition containing a flavonoid glycone and method for using same as anti-proliferative |
abstract |
The present invention relates generally to the use of a flavonoid glycone alone or in combination with a therapeutically effective amount of another agent such as an anti-keloid agent to inhibit, prevent or otherwise suppress keloid fibroblast proliferation and/or collagen synthesis. The subject invention further contemplates a method of ameliorating the effects of keloids such as keloid-mediated heavy or excessive scarring by the systemic or topical application of a flavonoid glycone alone or in combination with another agent such as an anti-keloid agent. The present invention is particularly directed to the use of quercetin as well as derivatives and homolog thereof. The present invention further provides medicaments comprising a flavonoid glycone such as quercetin and one or more other anti-keloid agents and/or agents which inhibit one or more components in the insulin-like growth factor (IGF) signalling cascade. Such medicaments may be in the form of a single composition or a multi-part pharmaceutical pack where the active ingredients are admixed prior to administration. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006060419-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2283831-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2281841-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2281841-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2283831-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7811562-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006138315-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8062886-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011157397-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7217796-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7667021-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7851181-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006060419-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008521907-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8017735-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7847068-B2 |
priorityDate |
2001-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |