| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b3c2e77f8dfda692ca527454d23ecc03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e4589b30807b53be5b8d5c09bfad19dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8b339aa6b581b1c47d5e6c9e07535bff |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00596
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-0072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00725
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00722
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00691
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-5027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-069
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0829
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0819
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00837
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00835
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00317
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-0086
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00743
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00497
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00364
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00585
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00527
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00536
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00533
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00644 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-0046
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-5085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-0093 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00 |
| filingDate |
2002-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a65790f1f0032b6a948a1f27b7654d3d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6993cd65c416c180fb3791673e4dcfcb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c68113a684623896a06560ddba748ad4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f46acf0c4d2b23a413867e966b2f60a1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f70f4153ac2bdeb9d2c0d18de531bab6 |
| publicationDate |
2003-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-03038404-A2 |
| titleOfInvention |
In vitro metabolic engineering on microscale devices |
| abstract |
Disclosed herein is a microfluidics device that can be used to prepare natural products and their analogs. The device comprises the enzymes of a biosynthetic pathway immobilized thereon and a means for sequentially directing a starting material and each ensuing reaction product to the enzymes of the biosynthetic pathway in the order corresponding to the steps of the biosynthetic pathway. The device can thus be used to prepare the natural product using the natural starting material of the biosynthetic pathway or analogs of the natural product using an unnatural starting material. Alternatively, artificial pathways can be created by immobilizing an appropriate selection of enzymes on the device in an order whereby each subsequent enzyme can catalyze a reaction with the product of the prior enzyme. Novel chemical entities can be prepared from these artificial pathways. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11629377-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2566986-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2568974-A |
| priorityDate |
2001-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |