| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff3e741d8c3082a79ba472a5a4c2bef8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f520441d84ae08a6e7e402d7332b3dd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_abb3ec5bd66af5ad0f3c03fd399abfe8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9059fb91e79718057a75e72ddc8847b3 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 |
| filingDate |
2002-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_864c6e756e94e23b0d199a6df3b4eb37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a147a3c3ddd362e6f1f2c34a6a278dc5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e75833cde4d19a40aeeabce7b42f5bf |
| publicationDate |
2003-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-03038121-A3 |
| titleOfInvention |
Method for the detection of cytosine methylation in immobilised dna samples |
| abstract |
A method for the detection of cytosine methylation in immobilised DNA samples is disclosed. In the first method step the genomic DNA is isolated from cells or other associated material and boned essentially irreversibly to a surface. The DNA bonded to the surface is then preferably treated with a bisulphite such that cytosine is converted into a base different from the base pairing relationship in the DNA duplex, whilst 5-methylcytosine remains unaltered. The used reagents are then removed in a washing step. Finally, selected sections of the immobilised DNA are amplified in a polymerase reaction and the amplificate examined with regard to the sequence thereof. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9249456-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9394565-B2 |
| priorityDate |
2001-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |