http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03031600-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_31a3b7f5b8f0bfdebec2b3a681879591 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c205bd504f23e24aac550e31f501e2e4 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-865 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-905 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 |
filingDate | 2001-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35925a4cd24373c003d951150d238bb7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ef05d47a9b1860597e5b122a0d12b8d |
publicationDate | 2003-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-03031600-A1 |
titleOfInvention | Saccharomyces-cerevisiae yeast strain with stable integration and expression of the nucleic acid sequence for a heterologous potassium ion channel |
abstract | The invention relates to <i>Saccharomyces-cerevisiae</i> yeast strains with a stable integration and expression of the nucleic acid sequence for a heterologous potassium ion channel, in addition to a method for constructing said yeast strains. In particular, the invention relates to a <i>Saccharomyces-cerevisiae</i> yeast strain, in which all identified potassium ion translocation systems have been specifically deleted and to a <i>Saccharomyces-cerevisiae</i> yeast strain, into which in addition a nucleic acid sequence, which codes for a heterologous potassium ion channel, in particular for a mammalian potassium ion channel such as the human erg potassium ion channel (HERG), is integrated in a stable manner into the yeast genome and is expressed. The invention also relates to a method for the stable integration of heterologous potassium ion channel proteins into a <i>Saccharomyces-cerevisiae</i> yeast strain and to a method for detecting specific modulators of mammalian potassium ion channels, using said yeast strains. |
priorityDate | 2001-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 387.