| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_22e3f121642d219dcf6a8f148ea9e2b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_234eeef0682525f0fd9c6ca670c66214
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b4978b1d99d5928086e344e6ddb5c36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_429ada5d3d958e4934c1a5d6461c3b33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f4ab5008f3611b00019bcfa2162ad22f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_918357680b87ea5353c2d00ac02f07ba |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6857
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y10-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y30-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate |
2002-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af7e9f863495b980c14909704d62d4d6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10c682ad6ab3361eab2839204d8d6f8c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d438c8e9ad949661d26df9605aad4488
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be6c6105bf2eea70bd7d5868d817e181
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4fa3fee9721b6c96148c072096cbfe0 |
| publicationDate |
2003-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-03030817-A2 |
| titleOfInvention |
Antibody complexes and methods for immunolabeling |
| abstract |
The present invention provides labeling reagents and methods for labeling primary antibodies and for detecting a target in a sample using an immuno-labeled complex that comprises a target-binding antibody and one or more labeling reagents. The labeling reagents comprise monovalent antibody fragments or non-antibody monomeric proteins whereby the labeling proteins have affinity for a specific region of the target-binding antibody and are covalently attached to a label. Typically, the labeling reagent is an anti-Fc Fab or Fab' fragment that was generated by immunizing a goat or rabbit with the Fc fragment of an antibody. The present invention provides for discrete subsets of labeling reagent and immuno-labeled complexes that facilitate the simultaneous detection of multiple targets in a sample wherein the immuno-labeled complexes are distinguished by i) a ratio of label to labeling reagent, or ii) a physical property of said label, or iii) a ratio of labeling reagent to said target-binding antibody, or iv) by said target-binding antibody. This is particularly useful for fluorophore labels that can be attached to labeling reagents and subsequently immuno-labeled complexes in ratios for the detection of multiple targets. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007047450-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8093012-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7282339-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10557851-B2 |
| priorityDate |
2001-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |