http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03029473-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_470a3cf04bb3bc920c36e851e7cc595d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_55c8f3df5ca45b3f3b41e47de5159888 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-102 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
filingDate | 2002-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b88d248cc7ae25c5bc75cd3c017518cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3284829e0acda61de43da23a796f18ba |
publicationDate | 2003-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-03029473-A1 |
titleOfInvention | Genetic tagging strategy for inducing and identifying mutations in a genomic sequence |
abstract | The invention features methods and compositions for introducing mutations in an endogenous host cell gene. In one embodiment, the invention features identification of genes that, when mutated, result in production of a phenotype of interest, e.g., tumor formation. In general, the invention provides a random mutagenesis system wherein a non-oncogenic, replicating vector acts as a vehicle to randomly introduce a construct comprising a hypermutation-inducing element into the genome of a host cell. Introduction of the hypermutation element in the host cell genome induces mutations (e.g., point mutations, small deletions, and/or small insertions) in genes adjacent to the integrated hypermutation element. |
priorityDate | 2001-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.