Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ce4a639c88dfdc46c25880af28c05b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d480ea6bf180d80ab3fad8bcf16b880f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bcc6a4e69daca1b8558d56ac94fe203e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_661c1d1ed4525bec43a9dae2c5557b90 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-02 |
filingDate |
2001-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a84a81a18e79a11cbb3ea9d40dc228b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c6bb6c07e3f7fd65acb0518419e4544 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fc7a740f5e41df94cc163eab0ecd5ab |
publicationDate |
2003-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-03027226-A2 |
titleOfInvention |
A method for producing antibody in avian species by intra-muscular injection of coding sequence |
abstract |
The present invention relates to processes for producing polyclonal antibody to an antigen in an avian species, preferably in a chicken, using intra-muscular injection of polynucleotide sequence followed by in vivo electroparation at the injection site. The coding sequence of a specific antigen linked to a promoter expresses the antigen. The level of antigen expression is sufficient enough to stimulate immune response and generate measurable antibody. Antibody is then purified from the injected animal. Comparing with other DNA vaccination methods, this method has the advantages of low cost, less stringent requirement of animal and environment, easy to operate, high reproducibility, and high success rate. It is more suitable for large-scale production of antibodies. |
priorityDate |
2000-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |