http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03027137-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e3ba7b8997168894047cc4ca560dcaa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f94cf07a461f1bc473f1bcfc85986c5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2ae703512ee7aaa1ffc422f74a0e05b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_929e8223605113d6cee4853915b5a8aa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70596 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-815 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-107 |
| filingDate | 2002-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc99001cc05e7be631b03ad0ab815ff9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf896b9d947ddbc643c303e49e8dfd1a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9f3a3380216ae692f834e70fdf55e2d |
| publicationDate | 2003-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-03027137-A3 |
| titleOfInvention | Trimeric conjugates of peptidic derivative |
| abstract | The invention provides a process for forming a compound having the formula (I): from chemical entities native [A], native [B] and native [C], where native [A] has a thioester group, native [B] had a 1-amino-2-thiol group with an unoxidised sulfhydryl side chain, and native [C] had a thiol reactive function (TRF) group, wherein chemical entities [A], [B] and [C] are covalently linked by linker group L, comprising the steps of: (i) admixing native [A] and native [B] in a reaction solution; (ii) condensing the unoxidised sulfydryl side chain of native [B] with the thioester group of native [A] for producing a first intermediate compound wherein [A] and [B] are linked with a β-aminothioester bond; (iii) rearranging the β-aminothioester bond for producing a second intermediate compound wherein [A] and [B] are linked with an amide bond having attached thereto a free thiol group; (iv) admixing native [C] with the second intermediate compound in a reaction solution; and (v) reacting the thiol reactive function (TRF) group of native [C] with the free thiol group of the second intermediate compound for producing a compound having the formula (I). |
| priorityDate | 2001-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 83.