| abstract |
The invention provides isolated nucleic acids molecules, designated 22417 nucleic acid molecules, which encode novel aminoprotease members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 22417 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 22417 gene has been introduced or disrupted. The invention still further provides isolated 22417 proteins, fusion proteins, antigenic peptides and anti-22417 antibodies. Diagnostic methods utilizing compositions of the invention are also provided. |