| abstract |
The present invention is in the field of molecular biology and genetics. More specifically, the invention relates to human ΔN p73, a novel gene associated with apoptosis regulation. The present invention provides and includes nucleic acid molecules, proteins and antibodies associated with ΔN p73 and methods utilizing such agents, for example in gene isolation, gene analysis, the production of transformed cell lines, and transgenic cells modified to over- or under-express ΔN p73. Moreover, the present invention includes use of the agents of the invention for the diagnosis, prevention and treatment of diseases associated with decreases or increased apoptosis. |