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filingDate 2002-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fd454bb82a34349617381d3ea7079a7
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publicationDate 2003-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-03021260-A3
titleOfInvention Method for gas chromatographic analysis of a urine sample
abstract Problem: It is desirable to provide a method for estimating the change of body smell with ageing by 1) utilization of the smell distinguishing ability of an experimental animal, 2) instrumental analysis, or 3) a combination of them.Solution: The present inventors found that the amounts of several volatile organic substances (e.g., 2-phenylacetamide, indole and phenol) present in mouse urine as substances responsible for the body smell are increased or decreased with ageing. The change in body smell with ageing of an animal can be estimated by quantitatively analyzing these compounds by an instrumental analysis method such as Y-shaped labyrinth method, gas chromatography (GC) or high-performance liquid chromatography (HPLC).
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