| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d486330b2483832d186f080650e837a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_96e719fb3eff234ea7dc7e272d97924d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0f4f8190960626ec922a1f03bcd4aba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4c377d69b98d2bd0c07e7c0c0008f0e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f15e05a0347d9e3329bf83f163da002d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-16 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-343
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C403-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C403-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C33-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-147
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C403-20 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C33-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-147
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C403-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-343
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C47-225 |
| filingDate |
2002-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_058663fbc8d3afde2e0e84ecd37faf26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_742b7d057c6a82618d6e45170d4e6c25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2f2c8155d2a728e16deff85c02ab0e5 |
| publicationDate |
2003-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-03018522-A3 |
| titleOfInvention |
Process for the preparation of beta-ionylideneacetaldehyde |
| abstract |
The present invention relates to an industrially advantageous process for the preparation of beta-ionylideneacetaldehyde of structural Formula I, which is a key intermediate for the synthesis of vitamin A and related compounds such as tretinoin and isotretinoin. The process involves : (a) condensing beta-ionone of structural Formula II with triethyl phosphonoacetate of structural Formula III to obtain ethyl beta-ionylideneacetate of structural Formula IV , (b) reducing the ester of Formula IV with a reducing agent to beta-ionylidene alcohol of Formula V in the presence of organic solvent,and (c) oxidizing the alcohol of Formula V in situ with manganese dioxide at 60-70°C for about 2 TO 4 hours to obtain beta-ionylideneacetaldehyde of structural Formula I . |
| priorityDate |
2001-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |