http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03016543-A3

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filingDate 2002-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2003-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-03016543-A3
titleOfInvention Enzymatic resolution of t-butyl taxane derivatives
abstract A method for the resolution of a mixture of the cis or trans enantiomers of a compound of the formula [insert chemical structure] wherein R1 is -O-C(O)alkyl, -O-C(O)aryl or -O-C(O)cycloalkyl by contacting the mixture with a carboxylic ester hydrolase enzyme which catalyzes the stereoselective hydrolysis of the mixture and the use of such enantiomers to produce antitumor compounds which are especially suitable for oral administration.
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