http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03012129-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7d3effb4e33b7ef461014fc9745df56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba1303ccef7c3a8ed8a6de0cf7459278 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-01071 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 |
| filingDate | 2002-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32274d2eb94e8c554e6928b718359806 |
| publicationDate | 2003-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-03012129-A3 |
| titleOfInvention | Shikimate kinase from s. aureus for drug discovery |
| abstract | A method for identification of an inhibitor of shikimate kinase activity and/or expression, which method comprises determining whether a test substance can inhibit: (I) activity of a polypeptide which comprises: (i) the amino acid sequence of SEQ ID NO:2; (ii) a variant thereof which is capable of shikimate kinase activity; or (iii) a fragment of (i) or (ii); and/or (II) transcription and/or translation of a polynucleotide encoding a polypeptide of (I); and/or (III) transcription and/or translation of a polynucleotide encoding a polypeptide capable of shikimate kinase activity and which polynucleotide comprises: (a) the nucleic acid sequence of SEQ ID NO: 1 and/or a sequence complementary thereto; (b) a sequence which hybridises under stringent conditions to a sequence as defined in (a); (c) a sequence that is degenerate as a result of the genetic code to a sequence as defined in (a) or (b); or (d) a sequence having at least 60 % identity to a sequence as defined in (a), (b) or (c). Inhibitors identified by such a method are useful in therapy, in particular in the treatment of microbial infections. |
| priorityDate | 2001-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.