| abstract |
The invention concerns various uses of a novel family of enzymes, called THYX, capable of catalyzing the synthesis of thymidine 5'-monophosphate in the absence of an active thymidylate synthase enzyme (ThyA). The invention also concerns reaction media for the thymidylate synthase activity of a THYX polypeptide and screening methods using said reaction media, as well as kits for implementing said methods. |