| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6854f76d82d8c84a7f2ddc6f91f8f2a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_acfe0c5a5279e0fdf79702dd7586d178
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a95aa041a99d6c9abf5df5ac1565372 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-3242
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-22 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-32 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16 |
| filingDate |
2002-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a6d4d3f4b824642f6c9a68bbd6af137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93aea594e90a3e3dee0eeb171be8a83d |
| publicationDate |
2003-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-03010512-A2 |
| titleOfInvention |
High-speed, solid-liquid separation |
| abstract |
An affinity separation and purification method and apparatus including (a) incubating reconstituted beads with a fluid containing low concentrations of a target compound; (b) introducing the loaded beads into an upstream circulating tank (5), connected with and feeding into a solid-liquid separation system, such as a high speed continuous centrifuge (C), having two additional ports (C2,C3), one (C2) communicating with downstream carrying solutes out of the loop (L) by the supernatant liquid, and the other (C3) communicating with the upstream and returning the concentrate back into the circulating tank (5), thereby effectively keeping the affinity beads within the loop (L); (c) concentrating the suspension of the incubated beads to a minimum volume that remains fluid and pumpable; and (d) diluting the concentrate in the circulating tank (5) with volumes of fresh buffer and continuing the centrifugation, thereby removing unbound, soluble byproducts and impurities in the supernatant. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11155575-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1942939-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113069790-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1942939-B1 |
| priorityDate |
2001-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |