| abstract |
The invention concerns the use, in preparing a medicine for inhibiting angiogenesis or invasion and/or formation of metastases, of an active agent selected among a proteinic substance comprising or consisting of all or part of the disintegrin domain of an adamalysin or a derivative thereof, a nucleic acid molecule comprising or consisting of a polynucleotide sequence encoding all or part of the disintegrin domain of an adamalysine or a derivative thereof. Advantageously, the adamalysin is metargidin. |