Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1f861d7dfdde7b233339d4838364a8e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2fe1022a05bd2114697d689defb0bbda http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4578ab271d6a6ed3e440755df5c3fa6d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55594 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55583 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1647 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 |
filingDate |
2002-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9506481cd9ac8edf1e21dd248a51e06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6e49874f2405afe1a4fab3d491ce992 |
publicationDate |
2003-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-03007869-A2 |
titleOfInvention |
Immunogenic compositions containing antigens, gene vectors and adjuvants-loaded biodegradable microspheres |
abstract |
The present invention relates to compositions which are able to stimulate an immune response in a host inoculated with an antigen of interest or the gene vector that codifies it. This composition includes microspheres based on copolymers derived from lactic acid glycolic acid encapsulating antigens, gene vectors and/or adjuvants with immunostimulatory properties obtained from mycobacterial fractions. The materialization of the present invention is the use of trehalose dimycolate associated to a heat shock protein or to the plasmid containing the gene that codifies it, encapsulated in microspheres with size smaller than 10 νm, capable of inducing specific antobodies and cellular immune responses, as well as the secretion of cytokines implicated in the protection against infectious diseases and cancer, following administration of a single dose or several doses. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014046983-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9636406-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10888618-B2 |
priorityDate |
2001-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |