http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03005301-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a219b763562e2f511e2ab8f50a4ef226 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_806e5cbc9e4a7498ae9f5d6dcf3fa8d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24a4787bb658b72044c995617c0cd9ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d33bddd7d6f8481f483e26f95dd44ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b00f9ef9c6a2bca2df82789fb5bdcf70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7d8f5849b81388947f316f9f5b99369 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5efc861be437a01e942224b241111bf9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate | 2002-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcd1b2b5c05344578ca203d7865f5929 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a455f8bcb55a23327bebc34f12041aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad576f4db2d607ea8f1226845fe64054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_582bb7978b0f512175301e73285e8760 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd7802b2a1c0873a107702a7ddb27e8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_429cc6428f17d82dc343a58e62f57561 |
| publicationDate | 2003-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-03005301-A1 |
| titleOfInvention | In vitro method of evaluating the biological activity of compounds on a large scale in suitable physiological or pathological conditions |
| abstract | The invention relates to the formation of blood vessels (angiogenesis); a process necessary for the growth and spread (metastasis) of tumours. The development of screening systems for the identification of compounds that inhibit said process represents an exhaustive research field which, in recent years, has been moving towards the use of computerised and robotised systems. The invention relates to an image acquisition and processing system which was designed and developed to be the nucleus of a platform intended for massive screening processes in experiments based on miniaturised in vitro angiogenesis models. Said system sequentially acquires and processes images of standard microplate cavities obtained using a microscope and digital camera. The invention also relates to a method of quantifying the degree of angiogenesis based on a morphological and topological analysis of the network of generated vessels which gives added value to the standard microvascular density parameter. Additional factors are taken into account in the calculation, such as vessel connectivity and length. The inventive system complies with the basic requirements of such experiments: objectivity, reproducibility and speed, which are achieved due to the automatic angiogenesis activity quantification capability developed. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8588492-B2 |
| priorityDate | 2001-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.