http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03002764-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9cea135f9cd881db94aea37be24fc63b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57446 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6897 |
| filingDate | 2002-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01fb53f4601b4503ffbf07d05ac60e95 |
| publicationDate | 2003-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-03002764-A2 |
| titleOfInvention | Screening method for identifying cancer therapy-relevant compounds |
| abstract | The invention relates to a method which allows to identify therapeutically useful compounds via the detection of the expression of glycoprotein antigens of the CEACAM family. The therapeutically useful compounds have properties that prevent the development of hyperplastic modifications that have been identified as precursors of a neoplastic transformation and that may lead to the formation of a carcinoma, or that reestablish a normalization of the tissue. The invention specifically relates to a method for identifying a compound/compounds that are useful in tumor prevention or for treating tumor precursors. The selected compounds are capable, by controlling gene expression, of increasing the apoptosis sensitivity of cells of the colon mucosa, especially of the precursor cells (or of reducing an apoptosis resistance). The invention further relates to a diagnostic method and to the use of the cells identified according to the invention in pharmaceutical compounds for preventing tumor formation and for treating the precursors thereof. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8309091-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007051805-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007051805-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1780220-A1 |
| priorityDate | 2001-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.