| abstract |
The invention refers to novel 2,3-benzodiazepine derivatives of formula (I) and pharmaceutical compositions containing the same as the active ingredient. The novel compounds have antipasmodic, muscle relaxant and neuroprotective activities. In formula I; X represents a hydrogen atom, a chloro atom or a methoxy group; Y stands for a hydrogen atom or a halo atom; Z means a methyl group or a chloro atom; R is a C1-4 alkyl group or a group of the formula -NR1R2, wherein R?1 and R2¿ represent, independently, a hydrogen atom, a C¿1-4? alkyl group, a C1-4 alkoxy group or a C?3-6¿ cycloalkyl group. |