abstract |
A multiple level micro-array system for integrating micro-arrays of biomolecules, including biological, chemical and biochemical elements. The multiple level micro-arrays are formed using soft lithography techniques and elastomeric membranes (1)b) to shield or pattern various portions of a suitable substrate (3) with biomolecules (8). Additional levels are formed using membranes (4) with various through holes (5) which either isolate, stratify or shield the patterned biomolecules from subsequent patterning or addition of an array solution. |