abstract |
A method of inhibiting infection by Flaviviridae viruses including HCV, GBC/HGV, and BVD in addition to VSV and any other virus capable of forming a complex with a lipoportein strategies: preventing formation of a complex should one form, altering the conforamtion of such a complex to prevent its interacton with the cell receptor, blocking the cell receptor for the complex using an antibody to the receptor, blocking binding of the lipoprotein complex to the cell receptor using soluble lipoprotein receptor or framents thereof, or downregulating the LDL receptor activity of the cells. |