Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ddb8c9f378ddf77eefdf4fda79cc794 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_abf33caa91c698a53b2d653874574765 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9afbf371d0c71641e337ecaebc83c427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea9e50062be48b529f7db10cf5cc3187 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ee354224a3910d5a9e898e3573c3ee7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6475 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 |
filingDate |
2001-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d43c35ec9ac9995090057e6f63520f78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c5c8cec46d6a4f8127ecafe0451d808 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a30438cadf1cbad27318ef066caf6b54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3502fe5dd11723349c8c2129ddcdd560 |
publicationDate |
2002-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0248329-A2 |
titleOfInvention |
Membrane derived caspase-3, compositions comprising the same and methods of use therefor |
abstract |
Provided are isolated nucleic acids encoding a novel membrane derived caspase-3 and polypeptides expressed therefrom. In one embodiment, the nucleic acid expression vectors that produce membrane derived caspase-3 polypeptide may be introduced into host cells as a gene delivery vehicle. In other embodiments, methods are provided for treating pathological disorders caused by altered apoptosis, such as autoimmune disease, cancer, viral infections, and bacterial infections. Another aspect of the invention is the use of the isolated nucleic acid encoding membrane derived caspase-3 and polypeptides expressed therefrom as a means for promoting or inhibiting programmed cell death. |
priorityDate |
2000-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |