| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78587acbfc8d4c9e9ac3baa7021087d7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4716 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6897 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
2001-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f44f32398af5b1c8c99229728647ae03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1dc88afa3b8d5df853bbd1a7a90fdd0e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f9dc2f1a48d781ff49c28e7768d9a8c |
| publicationDate |
2003-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0245659-A9 |
| titleOfInvention |
Novel therapeutics for heart failure and aging |
| abstract |
Myo/V1 is a cardiac-associated protein which interacts with NFλB, a well known stress-responsive cytoprotective transcription factor. Myo/V1 is upregulated during cardiac hypertrophy and heart failure. The present invention is directed to the function of Myo/V1 disruption of NFλB activity by promoting the formation of NFλB p50-p50 homodimers or p65-p65 homodimers, which results in altered adrenergic singlaing during these events. |
| priorityDate |
2000-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |