http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0241891-A3

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94ff2d78578d95d1e8d3a2233c76188d
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
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filingDate 2001-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61f58f5edd62a553088c40254f75f558
publicationDate 2003-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-0241891-A3
titleOfInvention Hiv treatment with benzimidazoles
abstract A pharmaceutical composition that can be used to treat HIV is disclosed. The composition comprising an effective amount of a benzimidazole of the formula: (I), wherein X is hydrogen, halogen, nitro, oxychloro alkyl of less than 7 carbon atoms or alkoxy of less than 7 carbon atoms; n is a positive integer of 4 or less; and R is hydrogen, alkylcarbamoyl wherein the alkyl group has less than 7 carbon atoms, or an alkyl group having from 1 to 8 carbon atoms, and R2 is NHCOOR1 wherein R1, is an aliphatic hydrocarbon of less than 7 carbon atoms. The pharmaceutically acceptable organic or inorganic addition salts thereof are also used herein. The preferred compounds are methyl-(butylcarbamoyl)-2benzimidazolecarbamate and 2-methoxycarbonylaminobenzimidazole. In the present invention it has been discovered that the compounds described above are useful for treatment of HIV infection when used alone or in combination with other anti-viral agents.
priorityDate 2000-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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