Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_26264c3039b8f0fcde4770bc40ff73f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a65b04eb409b671ed8eb878873aa1327 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_139cf0b99280b621554ebca1aca3461a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_151000070f06f2a592b4d32b0a31b913 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf1786a5456c1a2b278742daffe308c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b7ab75ff307cf36b45047c3e1793a6b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-96486 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
filingDate |
2001-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14b8bb1582d04ba6adbbd2ba64e46364 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecd5306bc351a124b46a1c3cd66669b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb8f1c2af6a731c5feede4f12aec44b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3817a96ba024d02d278c987044f2361 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cf46136d7da01fb7d0c18e2df651cbf |
publicationDate |
2002-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0241000-A1 |
titleOfInvention |
Immunoassay method for membrane-bound matrix metalloprotease |
abstract |
By using a simple procedure and a reagent, MT1-MMP can be quickly quantified or the enzymatic activity of MT1-MMP can be measured at a high sensitivity and a high accuracy. Namely, use of a method of immunologically quantifying MT1-MMP by using an anti-MT1-MMP antibody and a reagent to be used therefor; a method of immunologically quantifying a member selected from the group consisting of (i) MT1-MMP having been released and/or solubilized from cell membrane with the use of a surfactant and/or a reducing agent and (ii) autonomously solubilized MT1-MMP and a reagent to be used therefor; and solid-phase MT1-MMP makes it possible to quantify MT1-MMP or measure the enzymatic activity of MT1-MMP. Moreover, an MT1-MMP expression promoter or inhibitor and an MT1-MMP activity promoter or inhibitor can be screened thereby. Thus, research and development of useful drugs can be facilitated. These reagents are also useful in examining cancer and cancer metastasis. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102718840-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2004089419-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102718840-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004089419-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8349580-B2 |
priorityDate |
2000-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |