http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0238552-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f73837d9562fcb74893f03bba104ade http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e661e935570a989c3961925fd2cfb27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2aa388e460f6cf478bd46c925c6ab10e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f6971e8ec40e86dec71ac6cadf3aed3f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-023 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-023 |
| filingDate | 2001-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9c91bf29209d8686b2d6e6287e5cc78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1a3535d7631bc3b2202ec88966f7448 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecea70f61af94da3f140ab9cb971d755 |
| publicationDate | 2002-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-0238552-A1 |
| titleOfInvention | A novel method for the preparation of piperazine and its derivatives |
| abstract | The present invention describes a novel method for the synthesis of piperazine and its derivatives of formula (1), wherein R is selected from hydrogen or a lower alkyl (1 to 6 carbon atoms) group or a phenylalkyl group the alkyl of which has 1 to 4 carbon atoms; R1 is selected from hydrogen or a methyl group or a phenyl group optionally substituted with alkyl having 1 to 6 carbon atoms or a phenylalkyl group the alkyl of which has 1 to 4 carbon atoms and R2 is selected from hydrogen or a methyl group or a fluoromethyl group comprising the steps: a. reacting esters of formula (11) with substituted or unsubstituted ethylenediamine of formula (7) to give 3,4-dehydropiperazine-2-one and its derivatives of formula (12), wherein R, R1, R2 are as defined above and R6 is C1 to C4 linear or branched alkyl group; and b. reacting 3,4-dehydro-piperazine-2-one and its derivatives of formula (12) with a reducing agent to yield piperazine and its derivatives of formula (1). |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006022182-A1 |
| priorityDate | 2000-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 195.