| abstract |
The invention relates to the use of selectin-binding active ingredients, in the form of pregnancy proteins or fragments thereof, liposomes containing calcium-binding compounds, mucin fragments originating from native sources or derived from the same, or mimetic compounds imitating sialylated Lewis carbohydrate structures, or combinations thereof, for the treatment and prophylaxis of diseases in the development of which inflammatory processes play a role, for example, auto-immune diseases, transplantations, and arteriosclerosis. Inflammatory diseases in terms of the invention can be of an infectious or non-infectious nature. The invention also relates to the use of said active ingredients for partially or fully preventing the metastatic spread of tumours. The administration of the active ingredients can be carried out in a prophylactic manner or in conjunction with, for example, an ablation of the primary tumour or a biopsy. The invention further relates to the use of said active ingredients for the prophylaxis of tumor diseases. |