| abstract |
Preventives/remedies for portal hypertension containing compounds represented by the general formula (I), salts thereof or prodrugs of the same are provided. In said formula, R1 represents a group capable of forming an anion; X represents a bond or a spacer; n is an integer of 1 or 2; the ring A is an optionally substituted benzene ring; R2 represents a group capable of forming an anion; and R3 represents optionally substituted hydrocarbyl which may bonded via a hetero atom. These drugs are sufficiently excellent as medicines, since they have favorable preventive and therapeutic effects on portal hypertension without any side effect. |