abstract |
The invention relates to a method for determining skin stress and/or skin aging in humans or animals in vitro. The invention further relates to test kits for determining skin stress and/or skin aging and to the use of spondin 2, cathepsin L, vimentin fragments or actin gamma 1 as a stress and/or aging marker of the skin. The invention also relates to a method for analyzing the effectiveness of cosmetic or pharmaceutical active substances against skin stress and/or skin aging, and to agents for regulating, especially maintaining, homeostasis of human and animal skin. |