| abstract |
The invention provides isolated nucleic acids molecules, designated 23479, 48120, and 46689 nucleic acid molecules, which encode novel hydrolases. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 23479, 48120, and 46689 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 23479, 48120, or 46689 gene has been introduced or disrupted. The inventio still further provides isolated 23479, 48120, and 46689 proteins, fusion proteins, antigenic peptides and anti-23479, 48120, or 46689 antibodies. Diagnostic methods utilizing compositions of the invention are also provided. |