| abstract |
The invention provides isolated nucleic acids molecules, designated 22108 and 47916 nucleic acid molecules, which encode novel thioredoxin members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 22108 or 47916 nucleic and molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 22108 or 47916 gene has been introduced or disrupted. The invention still further provides isolated 22108 or 47916 proteins, fusion proteins, antigenic peptides and anti-22108 or 47916 antibodies. Diagnostic methods utilizing compositions of the invention are also provided. |