Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c45f41ecd18c39594f51cfdf2f0e8f3f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c9810bd80f90f4998edef6fd41770e8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_de3a933205363bce1a158e36bfe4d2ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c584c53d78f1687c7a99dffce9ccd435 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1034 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6837 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
filingDate |
2001-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f412d6b7d449ed9c03e107907595ad41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_916e5e1319736f880225b95bf6e7c5c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f10c97b382f5fdde44b264b04368968 |
publicationDate |
2002-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0222884-A2 |
titleOfInvention |
Microarrayed organization of transcription factor target genes |
abstract |
The following invention outlines methodologies for the construction and utilization of transcription factor direct target gene microarrays of both DNA and corresponding protein/peptide target origin. The technology entails the array/microarray annotation and organization of transcription factor direct loci and corresponding protein products identified through modified and improved versions of chromosomal immunoprecipitation (ChIP) and molecular cloning procedures. It allows for the formulation of physiologically directed arrays which result in a thorough, focused characterization of the genetic and biochemical regulation occurring within a give population of cells or a given tissue. Arrays and microarrays of direct targets for any given transcription factor created utilizing this technology are substantially more clinically relevant for purposes of medical diagnostics and patient prognostics than conventional microarrays due to the physiologically focused nature and the transcription factor targets. In addition, the characterization and array organization of transcription factor target protein products and the assessment of their interactions with other proteins and/or small molecules is of critical importance for the purposes of understanding cellular and organismal biology and ultimately the design of therapeutics for human anomalies. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7812124-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03043565-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1693466-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006086859-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006086859-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03043565-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009529855-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4913126-B2 |
priorityDate |
2000-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |