| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f84f1175f76e91a582a2a529df2dd9eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_add57ff5a849a69ec57951b3595a1696
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c487024cc7db63f1ee7d2a0a835cf92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9bceffddb90b9b3da8a772212961764b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_91e0f3f0b5cc3a7fdc1129d305d97165 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5091
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5041
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2001-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be5e1a6417311c6a29a9c217574c57bd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56051784bdcb498ec3b99f327dacaff7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1ce27e52e191960fac2d2248a3a28da |
| publicationDate |
2002-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0220770-A1 |
| titleOfInvention |
Method of screening antitumor agent by using interaction between arf protein and hk33 protein |
| abstract |
It is found out that HK33 protein binds to ARF protein. Nuclear transport of ARF protein is inhibited by the expression of HK33 gene and thus p53-dependent transcription is suppressed. In immortalized cells, moreover, the expression of HK33 gene is significantly elevated. A method of screening an antitumor agent by using the interaction between ARF protein and HK33 protein; a method of regulating HK33 protein-targeting signal transduction mediated by ARF protein and molecules employed therefor; and utilization of HK33 protein and a gene encoding HK33 protein in examining diseases such as tumor. Namely, it becomes possible to screen a novel antitumor agent with the use of the interaction between ARF protein and HK33 protein as an indication. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7625716-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009052942-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005054870-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105238833-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03087395-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03087395-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013526829-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012154938-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005054870-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105238833-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008513805-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7045913-B2 |
| priorityDate |
2000-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |