http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0218630-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9911f3ffb183144488431472d9039dfa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e78833eff5661b34183f21ce9a6b4464 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_385da2d5cb4ab8dbe81aefec4bfd2021 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2001-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_558509a408e8db3aeabfcbdeb7be8354 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f78b9f5d3cf1b2bd989ce4702f95be76 |
| publicationDate | 2002-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-0218630-A2 |
| titleOfInvention | Method of establishing resistance profiles of tissues and cell lines |
| abstract | The efficiency of the chemotherapy of malign diseases is limited by resistances vis-à-vis the cytostatics used, which resistances are mediated by a plurality of different mechanisms that proceed at the same time or sequentially. The invention relates to the use of a method of establishing resistance profiles using RNA from tissues or cell lines by way of real-time RT PCR technology (carried out, for example, on the "Light Cycler" of Roche Diagnostics GmbH). The invention allows a quantitative analysis of the expressions of different genes that are associated with the development or the intensification or the reduction of resistances. Based thereon it is, for example, possible to establish individual patient resistance profiles that form the molecular-biological base for the selection of appropriate cytostatics before and also during the particular tumor chemotherapy. The inventive method also allows a prognosis of the chances of success (response) of certain chemotherapeutical regimes. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1715041-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1550731-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1715041-A1 |
| priorityDate | 2000-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.