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filingDate 2001-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2002-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-0218588-A1
titleOfInvention Method for screening highly active proteases and inhibitors
abstract A method of screening a protease gene library for a gene encoding a protease of interest, the method comprising the steps of introducing a first gene of the protease gene library and a second gene encoding a protease inhibitor into a host cell; cultivating the host cell, wherein the cell expresses the first and the second genes to produce a complex of a protease and the inhibitor; dissociating the inhibitor from the complex; and selecting the protease of interest and isolating the encoding gene.
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