| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e798c9a2c1e8b19989d17c42ae9451cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_35cff44499631dd94d903093ccdfa484
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c3c9fc3cb0028234aedb8df651f9d2e4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6875 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
2001-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99c48ca616a7b9f041fc73ab860b8be2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a523e82ecb8ccc8103b9e1ee563d373 |
| publicationDate |
2002-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0218418-A1 |
| titleOfInvention |
Antibodies specific for methylated lysines in histones |
| abstract |
The present invention relates to the generation of methyllysine-specific histone antibodies. In particular, the H3 lysine 4 methylation specific antibody (Methyl(K4)H3) binds to histone H3 methylated at lysine 4. Methylation of lysine 4 (K4) on histone H3 has been associated with transcriptionally active regions of chromatin. A second antibody, H3 lysine 9 methylation specific antibody (Methyl(K9)H3) specifically binds to histone H3 methylated at lysine 9. Methylation of lysine 9 (K9) on histone H3 has been associated with gene silencing. These antibodies are useful in identifying regions of heterochromatin and euchromatin and serving as diagnostic and screening tools. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016038145-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10849965-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10564167-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1563093-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7074578-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7655431-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10441644-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005054296-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1483415-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1483415-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004080288-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11185577-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004080288-A2 |
| priorityDate |
2000-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |