| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36afc9a7a991fda247a0bd658f802da8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bedd17ebf078837f5a62aab18e5dd02b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0f4f8190960626ec922a1f03bcd4aba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_adb0b408e892ec23c7069e5360a64905 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 |
| filingDate |
2001-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6044da6fefd7caca0cb82a84233a09f2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a63775f3b5df3f82d9e70a6dc4fdd4b3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_292d2fde7d214ee3a5b4c47db1043dc2 |
| publicationDate |
2002-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0218366-A1 |
| titleOfInvention |
Process for the synthesis of n-(5-methylnicotinoyl)-4-hydroxypiperidine, a key intermediate of rupatadine |
| abstract |
The present invention relates to an improved and industrially advantageous process for the preparation of N-(5-methylnicotinoyl)-4-hydroxypiperidine of Formula I, as shown in the accompanied drawings. This compound is a key intermediate for the synthesis of rupatadine, a potent dual antagonist of histamine and platelet-activating factor (PAF). |
| priorityDate |
2000-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |