| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc62792656aa2e858252e97e5ffaca79 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-23 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-661
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1138
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-661
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2001-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e89c6f3b8aa1bc55563350c7c3c832e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a28e1f103c6af90887521a3d788fa8f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b19770e71b46b5ea91dde42c0a9f5034
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe4766037c0f804c6c1ca7164413f42b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_093a03d5e9e9b6f058f6d69d8f2d4492 |
| publicationDate |
2002-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0217899-A2 |
| titleOfInvention |
Regulation of angiogenesis via modulation of edg receptor mediated signal transduction comprising sphingosine-1-phosphate administration |
| abstract |
Methods for the inhibition of angiogenesis are presented, comprising affecting the response of the EDG-1 receptor by the administration of pharmaceutically effective antagonists of EDG-1 signal transduction. This invention is based in part on the discovery that Akt protein kinase phosphorylation is required for endothelial cell chemotaxis mediated by the EDG-1 G protein-coupled receptor. This invention relates to the use of modifiers of EDG-1 signal transduction to treat disorders of undesired angiogenesis. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1812797-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9274129-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004009816-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106170302-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106170302-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3135297-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1948234-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9274130-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2005325227-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1812797-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111484981-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9217749-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7862812-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1948234-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7794713-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009513668-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8791100-B2 |
| priorityDate |
2000-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |