http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0216935-A9
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4bacf06b40ae4ff695fd2e181bcea431 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e25122ca9e1f4111db033a05504ee3b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5bb107c0a798ef5bac4a74832fd9e5e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b01f557a719c49def005b8ae06777abf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3ecf622d11b6823fc081560487ab6fc2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_06c25e713df689b520ff27614aadf227 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-025 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
| filingDate | 2001-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d5c66b1cc9422a701df640e702ababd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_917c20fc85941ab321e7d1600ae33773 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_241c61c3a629ea9a5b15a3affe35379a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2a7adaa6d1a7c1b2f7b3c1e3ae12c34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f64db0819154daec3dc2dd70973e008c |
| publicationDate | 2003-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-0216935-A9 |
| titleOfInvention | Screening method for discovering auxiliary agents promoting endocytosis |
| abstract | The invention relates to a screening method for discovering auxiliary agents promoting the endocytosis of low molecular and/or macro-molecular compounds, especially nucleic acids, in cells. The inventive method comprises the following steps: a) a yeast strain is selected and yeast cells are cultivated therefrom; b) the yeast cells are incubated with a potential auxiliary agent promoting the endocytosis of low molecular and/or macro-molecular compounds, especially nucleic acids, in cells in addition to a nucleic acid which is replicable and/or replicable in the nucleus and/or in the cytosol of the yeast cells or a low molecular and/or macro-molecular compound, c) the transformation rates or the transport rates into the cytosol or the nucleus are determined and analysis occurs if the transformation rates or transport rates increase in comparison with the transformation rates and transport rates in a reference test in which the auxiliary substance is not used, d) the auxiliary substance is selected or rejected according to the result of the value obtained for the increase in the transformation rates or transport rates or transport rates in step c). The invention also relates to a screening method of the above-mentioned variety, wherein vertebrate cells are used, in addition to the use of auxiliary agents obtained according to said method in order to produce pharmaceutical substances. |
| priorityDate | 2000-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 109.