| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd7a91a1ceceb515d2d5064611d1e947
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ca59a543438e9c7dcd6620b2cb1bf43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_743d16c7c40435ab83e2b7dc4759dcb6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_30878c9ef56ddf33da0d24532e535018 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-36143 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1034
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 |
| filingDate |
2001-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7302fa9d07335e5464f1399d13fc0a14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43b9d4844b7a3c9d5c2958916874e65e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d382922f33854b7c91aebfa986440953 |
| publicationDate |
2002-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0216572-A2 |
| titleOfInvention |
Nucleic acid molecules, methods and kits for selecting a nucleic acid having a desired feature |
| abstract |
This invention relates to the use of a virus or of a viral genome for screening/selecting exogenous nucleic acids having a desired feature. More particularly, the present invention provides a dysfunctional viral genome capable of both expressing libraries of exogenous nucleic acids and selecting the sequences having a predefined characteristic or function within the cell, such as as nucleic acids encoding signal peptides, secreted proteins, membrane bound proteins, proteases, protease cleaving site and drug-resistance proteins. The invention further provides methods and kits for selecting nucleic acids having a desired feature. According to one embodiment, production of a viral particle is dependent on insertion of an exogenous nucleic acid having the desired feature into a dysfunctional viral genome or into a viral genome exposed to a substance inhibiting viral packaging function(s). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03002735-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03002735-A3 |
| priorityDate |
2000-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |