| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d50a7d8efd9b696f29a925f7973cf44e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d3b6e03a92d64f0e4893a8b297f7647
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08224b5a94dd3c65f6715c5cfa4881fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d5c168fab22bad3c1c02cfb4dbe8984e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa47f2ab053da109fec78edc1f952578
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc6e9a049924b7457350227978589a5e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f522311fa0f3c69aef1d87b84380fa45 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1242
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate |
2001-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9c835da5d656a61ba106271dd1fb072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8754d8fc89d13243902d98feee3dc218
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b568e61396bea920b1edcd400a565dd0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bfacf2b38809b24cbdd71354bb98be3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0340e0d904a46e36285dd394f62daea2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22ba159c23d8d7274a8b228a02443ad1 |
| publicationDate |
2002-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0216440-A2 |
| titleOfInvention |
Haemophilus influenzae lipopolysaccharide inner-core oligosaccharide epitopes as vaccines for the prevention of haemophilus influenzae infections |
| abstract |
The present invention relates to a lipopolysaccharide moiety comprising a conserved triheptosyl inner-core moiety of lipopolysaccharide substantially free of variable outer core oligosaccharide chain extension, and to vaccines obtaines therefrom which are cross-reactive for Haemophilus influenzae strains. The invention also relates to defined mutations in the biosynthetic machinery for lipopolysaccharide (LPS) expression in Haemophilus influenzae useful to obtain the abovementioned moiety. The invention also relates to using conjugates of the LPS from the mutant strains so obtained to elicit a heterologous immune response against a wide range of disease-causing H. influenzae strains. More specifically, the invention relates to vaccines for prevention of bacterial infections comprising core lipopolysaccharide of Haemophilus influenzae. A lipopolysaccharide moiety comprising a conserved triheptosylinner-core moiety of lipopolysaccharide substantially free of variable outer core oligosaccharide chain extensions. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008106763-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016007891-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005111196-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1747262-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8920814-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1747262-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7759070-B2 |
| priorityDate |
2000-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |