http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0216438-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e1018b924ad1e238642eaad9d2172a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e48dac932505109472e62e4538d64909 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2cc50ebbed1194b4a87e76e385d499f0 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H3-06 |
filingDate | 2001-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_501b0d67afc52965bb257ed309e614d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c980cc1753d42881c5233071dd440683 |
publicationDate | 2002-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-0216438-A2 |
titleOfInvention | Synthesis of complex carbohydrates |
abstract | A tailor-assembly approach is employed for synthesis of complex carbohydrates wherein a polysaccharide is degraded and the shorter product obtained from the degradation is subjected to enzymatic modification to add a sugar moiety. The products may be useful in the preparation of a cancer vaccine. In one example, oligosaccharides of the type Ia group B Streptococcus (GBSIa) capsular polysaccharide and multivalent sialyl Lex antigens are specifically described. GBSIa polysaccharide was depolymerized by partial Smith degradation to fragments representing asialo core repeating units. Enzymatic sialylation of these oligomers furnished GBSIa repeating units (from monomer to pentamer). Fucosylation on GlcNAc residues of GBSIa oligomers afforded oligosaccharides that carry multiple sialyl Lex epitopes. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004041291-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005037187-A3 |
priorityDate | 2000-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 128.