| abstract |
Piperidine derivatives represented by the following general formula (I) (wherein each symbol has the meaning as defined in the description) or nontoxic salts thereof. Because of having a PDE4 inhibitory activity, the compounds represented by the general formula (I) are useful in preventing and/or treating inflammatory diseases, diabetic diseases, allergic diseases, autoimmune diseases, osteoporosis, bone fracture, obesity, depression, Parkinson's disease, ischemic reperfusion failure, leukemia, etc. |